At the other end of the spectrum are the opponents of reductionism who are appalled by what they feel to be the bleakness of modern science. To whatever extent they and their world can be reduced to a matter of particles or fields and their interactions, they feel diminished by that knowledge…I would not try to answer these critics with a pep talk about the beauties of modern science. The reductionist worldview is chilling and impersonal. It has to be accepted as it is, not because we like it, but because that is the way the world works.
Dreams of a Final Theory, Steven Weinberg